Publications

  1. Pires AS, Porto WF, Castro PO, Franco OL, Alencar SA. Theoretical structural characterization of lymphoguanylin: A potential candidate for the development of drugs to treat gastrointestinal disorders. J Theor Biol. 2017;419: 193-200. doi:10.1016/j.jtbi.2017.02.016
  2. Porto WF, Pires AS, Franco OL. Computational tools for exploring sequence databases as a resource for antimicrobial peptides. Biotechnol Adv. 2017;35. doi:10.1016/j.biotechadv.2017.02.001
  3. Porto WF, Pires AS, Franco OL. Antimicrobial activity predictors benchmarking analysis using shuffled and designed synthetic peptides. J Theor Biol. 2017;426: 96-103. doi:10.1016/j.jtbi.2017.05.011
  4. De Jesus Miranda V, Porto WF, Da Rocha Fernandes G, Pogue R, Nolasco DO, Guerra Araujo AC, et al. Comparative transcriptomic analysis indicates genes associated with local and systemic resistance to Colletotrichum graminicola in maize. Sci Rep. 2017;7. doi:10.1038/s41598-017-02298-8
  5. Pires AS, Porto WF, Franco OL, Alencar SA. In silico analyses of deleterious missense SNPs of human apolipoprotein E3. Sci Rep. 2017;7: 2509. doi:10.1038/s41598-017-01737-w
  6. Porto WF, Marques FA, Pogue HB, de Oliveira Cardoso MT, do Vale MGR, da Silva Pires A, et al. Computational Investigation of Growth Hormone Receptor Trp169Arg Heterozygous Mutation in a Child With Short Stature. J Cell Biochem. 2017;118: 4762-4771. doi:10.1002/jcb.26144
  7. Fleitas Martinez O, Rigueiras PO, Pires A da S, Porto WF, Silva ON, de la Fuente-Nunez C, et al. Interference With Quorum-Sensing Signal Biosynthesis as a Promising Therapeutic Strategy Against Multidrug-Resistant Pathogens. Front Cell Infect Microbiol. 2019;8. doi:10.3389/fcimb.2018.00444
  8. Porto WF, Irazazabal L, Alves ESF, Ribeiro SM, Matos CO, Pires AS, et al. In silico optimization of a guava antimicrobial peptide enables combinatorial exploration for peptide design. Nat Commun. 2018;9: 1490. doi:10.1038/s41467-018-03746-3
  9. Porto WF, Fensterseifer ICM, Ribeiro SM, Franco OL. Joker: An algorithm to insert patterns into sequences for designing antimicrobial peptides. Biochim Biophys Acta – Gen Subj. 2018;1862. doi:10.1016/j.bbagen.2018.06.011
  10. Silva ON, Porto WF, Ribeiro SM, Batista I, Franco OL. Host-defense peptides and their potential use as biomarkers in human diseases. Drug Discov Today. 2018;23: 1666-1671. doi:10.1016/j.drudis.2018.05.024
  11. Cardoso M, Candido E, Chan L, Torres MDT, Oshiro K, Rezende S, et al. A computationally designed peptide derived from Escherichia coli as a potential drug template for antibacterial and antibiofilm therapies. ACS Infect Dis. 2018; acsinfecdis.8b00219. doi:10.1021/acsinfecdis.8b00219
  12. Silva ON, Franco OL, Porto WF. Beta-lactamase inhibitor peptides as the new strategies to overcome bacterial resistance. Drugs of Today. 2018;54: 737. doi:10.1358/dot.2018.54.12.2895652
  13. Irazazabal LN, Porto WF, Fensterseifer ICM, Alves ESF, Matos CO, Menezes ACS, et al. Fast and potent bactericidal membrane lytic activity of PaDBS1R1, a novel cationic antimicrobial peptide. Biochim Biophys Acta – Biomembr. 2018. doi:10.1016/J.BBAMEM.2018.08.001
  14. Candido ES, Cardoso MH, Chan LY, Torres MDT, Oshiro KGN, Porto WF, et al. Short Cationic Peptide Derived from Archaea with Dual Antibacterial Properties and Anti-Infective Potential. ACS Infect Dis. 2019;5: 1081-1086. doi:10.1021/acsinfecdis.9b00073
  15. Pires AS, Rigueiras PO, Dohms SM, Porto WF, Franco OL. Structure-guided identification of antimicrobial peptides in the spathe transcriptome of the non-model plant, arum lily (Zantedeschia aethiopica). Chem Biol Drug Des. 2019. doi:10.1111/cbdd.13498
  16. Fensterseifer ICM, Felicio MR, Alves ESF, Cardoso MH, Torres MDT, Matos CO, et al. Selective antibacterial activity of the cationic peptide PaDBS1R6 against Gram-negative bacteria. Biochim Biophys Acta – Biomembr. 2019. doi:10.1016/j.bbamem.2019.03.016
  17. Oshiro KGN, Candido ES, Chan LY, Torres MDT, Monges BED, Rodrigues SG, et al. Computer-Aided Design of Mastoparan-like Peptides Enables the Generation of Nontoxic Variants with Extended Antibacterial Properties. J Med Chem. 2019;62: 8140-8151. doi:10.1021/acs.jmedchem.9b00915
  18. Cardoso MH, Santos VPM, Costa BO, Buccini DF, Rezende SB, Porto WF, et al. A short peptide with selective anti-biofilm activity against Pseudomonas aeruginosa and Klebsiella pneumoniae carbapenemase-producing bacteria. Microb Pathog. 2019;135: 103605. doi:10.1016/j.micpath.2019.103605
  19. Monteiro LLS, Franco OL, Alencar SA, Porto WF. Deciphering the structural basis for glucocorticoid resistance caused by missense mutations in the ligand binding domain of glucocorticoid receptor. J Mol Graph Model. 2019;92: 216-226. doi:10.1016/j.jmgm.2019.07.020